Title : Tumor suppressor protein p53 binds preferentially to supercoiled DNA.

Pub. Date : 1997 Oct

PMID : 9393978






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Wild type human tumor suppressor protein p53 (expressed in insect cells) binds strongly to negatively supercoiled (sc) plasmid DNA at a native superhelix density, as evidenced by electrophoretic retardation of scDNA in agarose gels and imaging by scanning force microscopy (SFM). Sepharose tumor protein p53 Homo sapiens