Title : Dinitrosyl-dithiol-iron complexes, nitric oxide (NO) carriers in vivo, as potent inhibitors of human glutathione reductase and glutathione-S-transferase.

Pub. Date : 1997 Dec 15

PMID : 9393673






1 Functional Relationships(s)
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1 Absorption spectra of inhibited GR showed that the charge-transfer interaction between the isoalloxazine moiety of the prosthetic group flavin adenine dinucleotide (FAD) and the active site thiol Cys63 is disturbed by the modification. isoalloxazine glutathione-disulfide reductase Homo sapiens