Title : An intranasal glucocorticoid inhibits the increase of specific IgE initiated during birch pollen season.

Pub. Date : 1997 Nov

PMID : 9389288






3 Functional Relationships(s)
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1 Both the treatment group and the placebo group showed a trend of an increase in anti-birch IgE levels 2 weeks after the beginning of the treatment (from 33.1 +/- 13.1 kU/L to 44.9 +/- 20.9 kU/L in the beclomethasone group and from 53.2 +/- 18.9 kU/L to 64.1 +/- 22.1 kU/L in the placebo group). Beclomethasone immunoglobulin heavy constant epsilon Homo sapiens
2 Treatment with beclomethasone returned anti-birch IgE levels to baseline by the end of the study, whereas in the placebo group the anti-birch IgE levels continued to increase (final values, 33.1 +/- 11.9 kU/L vs 72.6 +/- 23.2 kU/L, respectively). Beclomethasone immunoglobulin heavy constant epsilon Homo sapiens
3 The change in IgE antibody levels in the placebo group was significantly higher than that in the beclomethasone group. Beclomethasone immunoglobulin heavy constant epsilon Homo sapiens