Title : Gene therapy with modified tumor cells enables T-cell activation by stimulating pathways required for signal transduction.

Pub. Date : 1996 Sep

PMID : 9384701






2 Functional Relationships(s)
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1 Western blotting following stimulation of T cells with parental or genetically engineered IL-2-secreting, B7+ tumor cells revealed increased protein tyrosine phosphorylation in lysates derived from ITB compared with PTB T cells, demonstrating that tumor-derived IL-2 could influence signaling. Tyrosine interleukin 2 Mus musculus
2 Western blotting following stimulation of T cells with parental or genetically engineered IL-2-secreting, B7+ tumor cells revealed increased protein tyrosine phosphorylation in lysates derived from ITB compared with PTB T cells, demonstrating that tumor-derived IL-2 could influence signaling. Tyrosine interleukin 2 Mus musculus