Title : The involvement of CYP1A2 and CYP3A4 in the metabolism of clozapine.

Pub. Date : 1997 Nov

PMID : 9384460






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Formation of DCLZ was inhibited by fluvoxamine (53 +/- 28% at 10 microM), triacetyloleandomycin (33 +/- 15% at 10 microM), and ketoconazole (51 +/- 28% at 2 microM) and by antibodies against CYP1A2 and CYP3A4. Ketoconazole cytochrome P450 family 1 subfamily A member 2 Homo sapiens