Title : The effects of epidermal growth factor, interleukin-1, and phenytoin, alone and in combination, on C19 steroid conversions in fibroblasts.

Pub. Date : 1997 Sep

PMID : 9379324






2 Functional Relationships(s)
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1 In the cell lines studied, EGF stimulated DHT and 4-androstenedione synthesis by 20% (n = 5; P < 0.01; Wilcoxon signed rank statistic for paired observations). Androstenedione epidermal growth factor Homo sapiens
2 Combinations of phenytoin and EGF stimulated DHT and 4-androstenedione synthesis by 33% and 37% greater than the effect of phenytoin alone (n = 3; P < 0.01). Androstenedione epidermal growth factor Homo sapiens