Pub. Date : 1997 Aug
PMID : 9378721
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Role of the pyrrolidine ring of proline in determining the substrate specificity of cdc2 kinase or cdk5. | Proline | cyclin dependent kinase 5 | Homo sapiens |
| 2 | For cdk5, these substitutions led to parallel effects on the K(m) value to those found for cdc2 kinase; cdk5 recognized the peptides with a proline specificity similar to that for cdc2 kinase. | Proline | cyclin dependent kinase 5 | Homo sapiens |
| 3 | For cdk5, these substitutions led to parallel effects on the K(m) value to those found for cdc2 kinase; cdk5 recognized the peptides with a proline specificity similar to that for cdc2 kinase. | Proline | cyclin dependent kinase 5 | Homo sapiens |
| 4 | These results suggest that the pyrrolidine ring of proline is important for substrate recognition by cdc2 kinase or cdk5. | Proline | cyclin dependent kinase 5 | Homo sapiens |
| 5 | The results obtained here also suggest that the pyrrolidine ring of proline is required to maintain a high V(max) value for cdc2 kinase or especially for cdk5. | Proline | cyclin dependent kinase 5 | Homo sapiens |