Title : Mechanisms of cycloheximide-induced apoptosis in liver cells.

Pub. Date : 1997 Oct 13

PMID : 9369245






1 Functional Relationships(s)
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1 Cycloheximide in sublethal doses caused apoptosis in liver cells in vivo, inducing c-myc, c-fos, c-jun and p53 genes and accumulation of sphingosine, a toxic product of the sphingomyelin cycle. Cycloheximide Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens