Title : Cluster mannosides can inhibit mannose receptor-mediated tissue-type plasminogen activator degradation by both rat and human cells.

Pub. Date : 1997 Nov

PMID : 9362376






3 Functional Relationships(s)
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1 Cluster mannosides can inhibit mannose receptor-mediated tissue-type plasminogen activator degradation by both rat and human cells. Mannosides plasminogen activator, tissue type Rattus norvegicus
2 The mannoside with the highest affinity was able to inhibit t-PA clearance by the liver in the rat. Mannosides plasminogen activator, tissue type Rattus norvegicus
3 The mannosides do inhibit mannose receptor-mediated t-PA binding, association, and degradation by isolated rat liver endothelial cells and t-PA association and degradation by cultured human macrophages at similar concentrations. Mannosides plasminogen activator, tissue type Rattus norvegicus