Title : dUTP pyrophosphatase as a potential target for chemotherapeutic drug development.

Pub. Date : 1997

PMID : 9360704






1 Functional Relationships(s)
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1 While considerable effort has been directed towards discovering new, more potent inhibitors of these two enzymes, little attention has been given dUTP pyrophosphatase (dUTPase)--the key modulator of cellular dUTP levels--as a potential target for chemotherapeutic drug development. deoxyuridine triphosphate Deoxyuridine triphosphatase Drosophila melanogaster