Title : Tissue factor is induced by monocyte chemoattractant protein-1 in human aortic smooth muscle and THP-1 cells.

Pub. Date : 1997 Nov 7

PMID : 9353321






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Chelation of intracellular calcium and inhibition of protein kinase C block the induction of TF by MCP-1, suggesting that in SMC it is mediated by activation of phospholipase C. SMC bind MCP-1 with a Kd similar to that previously reported for macrophages. Calcium C-C motif chemokine ligand 2 Homo sapiens
2 Chelation of intracellular calcium and inhibition of protein kinase C block the induction of TF by MCP-1, suggesting that in SMC it is mediated by activation of phospholipase C. SMC bind MCP-1 with a Kd similar to that previously reported for macrophages. Calcium C-C motif chemokine ligand 2 Homo sapiens