Title : Chemokine secretion by human polymorphonuclear granulocytes after stimulation with Mycobacterium tuberculosis and lipoarabinomannan.

Pub. Date : 1997 Nov

PMID : 9353042






1 Functional Relationships(s)
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1 Treatment of PNG with the leukotriene-B4 inhibitor MK-886 prior to stimulation with M. tuberculosis or LAM partially blocked IL-8 and GRO-alpha induction, suggesting involvement of the 5-lipoxygenase pathway in the secretion of these chemokines. MK-886 C-X-C motif chemokine ligand 8 Homo sapiens