Title : Diethyldithiocarbamate and nitric oxide synergize with oxidants and with membrane-damaging agents to injure mammalian cells.

Pub. Date : 1997 Aug

PMID : 9350419






1 Functional Relationships(s)
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1 The addition to these reaction mixtures of subtoxic amounts of DDC (an SOD inhibitor and a copper chelator) not only very markedly enhanced cell death but also resulted in the release of large amounts of arachidonate (in the complete absence of added proteinases). Ditiocarb superoxide dismutase 1 Homo sapiens