Title : Role of nitric oxide in the convulsive seizures induced by fluoroquinolones coadministered with 4-biphenyl acetic acid.

Pub. Date : 1997 Nov

PMID : 9347323






1 Functional Relationships(s)
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1 Pretreatment with the nitric oxide synthase (NOS) inhibitor, NG-nitro-L-arginine methylester (L-NAME), but not with D-NAME, significantly reduced the incidence of convulsions and lethality, as well as the increase in cyclic GMP. Nitroarginine nitric oxide synthase 1, neuronal Mus musculus