Title : Ara-C: cellular and molecular pharmacology.

Pub. Date : 1998

PMID : 9338077






1 Functional Relationships(s)
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1 First, the activity of ara-C depends on conversion to its lethal triphosphate derivative, ara-CTP, a process that is influenced by multiple factors, including nucleoside transport, phosphorylation, deamination, and levels of competing metabolites, particularly dCTP. triphosphoric acid solute carrier family 25 member 1 Homo sapiens