Title : High-dose cyclophosphamide for poor-prognosis and recurrent pediatric brain tumors: a dose-escalation study.

Pub. Date : 1997 Oct

PMID : 9336363






1 Functional Relationships(s)
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1 PURPOSE: To determine the maximum-tolerated dose (MTD) of cyclophosphamide (CTX) when administered over 2 consecutive days followed by hematopoetic stem-cell rescue given as two sequential courses to children with glioblastoma multiforme, poor-prognosis pontine gliomas, and other recurrent CNS tumors. Cyclophosphamide cytochrome P450 family 27 subfamily A member 1 Homo sapiens