Title : Endothelial nitric oxide synthase-dependent superoxide generation from adriamycin.

Pub. Date : 1997 Sep 23

PMID : 9333325






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Endothelial nitric oxide synthase-dependent superoxide generation from adriamycin. Superoxides nitric oxide synthase 3 Homo sapiens
2 Adriamycin binds to eNOS with a Km of approximately 5 microM, as calculated from both eNOS-dependent NADPH consumption and superoxide generation. Superoxides nitric oxide synthase 3 Homo sapiens
3 A consequence of eNOS-mediated reductive activation of adriamycin is the disruption of the balance between nitric oxide and superoxide. Superoxides nitric oxide synthase 3 Homo sapiens