Title : Bioactivation of the anticancer agent CPT-11 to SN-38 by human hepatic microsomal carboxylesterases and the in vitro assessment of potential drug interactions.

Pub. Date : 1997 Oct

PMID : 9321519






1 Functional Relationships(s)
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1 The inhibitors BNPP (360 microM) and NaF (500 microM) inhibited alpha-naphthol formation to 9-10% of control and to 14-20% of control, respectively. 1-naphthol C-X-C motif chemokine ligand 8 Homo sapiens