Title : Phosphorylation of the Src substrate Sam68 by Cdc2 during mitosis.

Pub. Date : 1997 Sep

PMID : 9315091






1 Functional Relationships(s)
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1 Cdc2 was identified as the kinase responsible for the mitotic threonine phosphorylation by (1) immunodepletion of the mitotic Sam68 kinase from cell lysates with anti-Cdc2 antibodies, (2) inhibition of Sam68 phosphorylation in vitro and in vivo by the cyclin-dependent kinase inhibitor olomoucine and (3) phosphorylation of Sam68 by purified Cdc2. olomoucine cyclin dependent kinase 1 Homo sapiens