Title : Defining GC-specificity in the minor groove: side-by-side binding of the di-imidazole lexitropsin to C-A-T-G-G-C-C-A-T-G.

Pub. Date : 1997 Aug 15

PMID : 9309219






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Side-by-side Im and Py rings differentiate GC from CG base pairs because of tight steric contacts and sp2 hybridization at the amine nitrogen atom, with the favored conformations being G/Im,Py/C and C/Py,Im/G. Amines Sp2 transcription factor Homo sapiens