Pub. Date : 1997 Sep
PMID : 9307976
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To investigate the mechanism of cell cycle inhibition by p27Kip1, we constructed a cell line that inducibly expresses p27Kip1 upon addition of isopropyl-1-thio-beta-D-galactopyranoside in the culture medium. | Isopropyl Thiogalactoside | cyclin dependent kinase inhibitor 1B | Homo sapiens |
| 2 | To investigate the mechanism of cell cycle inhibition by p27Kip1, we constructed a cell line that inducibly expresses p27Kip1 upon addition of isopropyl-1-thio-beta-D-galactopyranoside in the culture medium. | Isopropyl Thiogalactoside | cyclin dependent kinase inhibitor 1B | Homo sapiens |
| 3 | Isopropyl-1-thio-beta-D-galactopyranoside-induced expression of p27Kip1 in these cells causes a specific reduction in the expression of the E2F-regulated genes such as cyclin E, cyclin A, and dihydrofolate reductase. | Isopropyl Thiogalactoside | cyclin dependent kinase inhibitor 1B | Homo sapiens |