Title : Efficacy of danazol in a patient with congenital protein-S deficiency: paradoxical evidence for decreased platelet activation with increased thrombin generation.

Pub. Date : 1997 Sep 1

PMID : 9306621






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Following danazol administration, marked and sustained increases were noted in Free Protein S, Antithrombin, and Protein C. Platelet CD62 (P-selectin) positivity which was elevated before therapy, decreased to assay threshold limits within five weeks. Danazol serpin family C member 1 Homo sapiens
2 Both Prothrombin Fragment 1.2 and thrombin-antithrombin complexes were elevated post danazol therapy indicating continued clearance of generated thrombin. Danazol serpin family C member 1 Homo sapiens