Title : Regulation of glucose transport by interleukin-3 in growth factor-dependent and oncogene-transformed bone marrow-derived cell lines.

Pub. Date : 1997 Jul

PMID : 9301681






7 Functional Relationships(s)
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1 Regulation of glucose transport by interleukin-3 in growth factor-dependent and oncogene-transformed bone marrow-derived cell lines. Glucose interleukin 3 Mus musculus
2 This study aimed to investigate growth factor regulation of glucose transport in an interleukin (IL)-3-dependent bone marrow-derived cell line and its oncogene-transformed counterparts. Glucose interleukin 3 Mus musculus
3 IL-3 stimulated glucose uptake in both control and oncogene-transformed cells. Glucose interleukin 3 Mus musculus
4 With control and ras-transformed cells, enhanced glucose uptake in response to IL-3 was associated with increased affinity of glucose transporters for glucose but with abl-transformed cells, no significant affinity changes were observed. Glucose interleukin 3 Mus musculus
5 With control and ras-transformed cells, enhanced glucose uptake in response to IL-3 was associated with increased affinity of glucose transporters for glucose but with abl-transformed cells, no significant affinity changes were observed. Glucose interleukin 3 Mus musculus
6 IL-3 also increased glucose transporter expression in both control and oncogene-transformed cells, suggesting that increased transporter expression as well as changes in transporter affinity for glucose can affect glucose uptake. Glucose interleukin 3 Mus musculus
7 IL-3 also increased glucose transporter expression in both control and oncogene-transformed cells, suggesting that increased transporter expression as well as changes in transporter affinity for glucose can affect glucose uptake. Glucose interleukin 3 Mus musculus