Pub. Date : 1997 Jul 30
PMID : 9298921
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Differential effect of haloperidol on release of neurotensin in extrapyramidal and limbic systems. | Haloperidol | neurotensin | Homo sapiens |
| 2 | The effect of the antipsychotic drug haloperidol on extracellular neurotensin-like immunoreactivity was investigated by microdialysis and compared with the time-dependent response of tissue neurotensin-like immunoreactivity content in brain structures containing dopamine nerve cell bodies and terminals. | Haloperidol | neurotensin | Homo sapiens |
| 3 | A single administration of haloperidol (1 mg/kg) increased the extracellular neurotensin-like immunoreactivity levels in nucleus accumbens as measured by microdialysis, but decreased its extracellular concentration in the caudate regions surrounding the probe. | Haloperidol | neurotensin | Homo sapiens |
| 4 | These findings suggest that varied neurotensin systems are associated with nigrostriatal and mesolimbic dopamine pathways and these systems have different responses to haloperidol. | Haloperidol | neurotensin | Homo sapiens |
| 5 | The changes in the release of neurotensin may contribute to altered caudate and accumbens neurotensin-like immunoreactivity tissue content induced by haloperidol treatment, but other factors, such as variation in synthesis also likely influence these effects. | Haloperidol | neurotensin | Homo sapiens |
| 6 | The changes in the release of neurotensin may contribute to altered caudate and accumbens neurotensin-like immunoreactivity tissue content induced by haloperidol treatment, but other factors, such as variation in synthesis also likely influence these effects. | Haloperidol | neurotensin | Homo sapiens |
| 7 | Differential actions of haloperidol on neurotensin release might be due to regional differences in dopamine or sigma receptor subtypes associated with the neurotensin-containing neurons. | Haloperidol | neurotensin | Homo sapiens |
| 8 | Differential actions of haloperidol on neurotensin release might be due to regional differences in dopamine or sigma receptor subtypes associated with the neurotensin-containing neurons. | Haloperidol | neurotensin | Homo sapiens |