Title : Applications of primary human hepatocytes in the evaluation of pharmacokinetic drug-drug interactions: evaluation of model drugs terfenadine and rifampin.

Pub. Date : 1997 Jul

PMID : 9298257






1 Functional Relationships(s)
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1 Induction of CYP3A4, measured as testosterone 6 beta-hydroxylation, was found to be dose-dependent, treatment duration-dependent, and reversible. Testosterone cytochrome P450 family 3 subfamily A member 4 Homo sapiens