Title : 25-Hydroxyvitamin D3 1alpha-hydroxylase and vitamin D synthesis.

Pub. Date : 1997 Sep 19

PMID : 9295274






2 Functional Relationships(s)
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1 Renal 25-hydroxyvitamin D3 1alpha-hydroxylase [1alpha(OH)ase] catalyzes metabolic activation of 25-hydroxyvitamin D3 into 1alpha, 25-dihydroxyvitamin D3 [1alpha,25(OH)2D3], an active form of vitamin D, and is inhibited by 1alpha,25(OH)2D3. Vitamin D cytochrome P450, family 27, subfamily b, polypeptide 1 Mus musculus
2 These results indicate that the negative feedback regulation of active vitamin D synthesis is mediated by 1alpha(OH)ase through liganded VDR. Vitamin D cytochrome P450, family 27, subfamily b, polypeptide 1 Mus musculus