Title : Regulatory role of prostaglandin E2 in induction of cyclo-oxygenase-2 by a thromboxane A2 analogue (U46619) and basic fibroblast growth factor in porcine aortic smooth-muscle cells.

Pub. Date : 1997 Sep 1

PMID : 9291137






2 Functional Relationships(s)
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1 However, activation of ERK2 by FGF-2 was not affected by PGE2 whereas that of JNK1 by U46619 was inhibited, suggesting that inhibition of COX-2 expression by cAMP may be downstream of ERK2. Cyclic AMP mitogen-activated protein kinase 1 Homo sapiens
2 However, activation of ERK2 by FGF-2 was not affected by PGE2 whereas that of JNK1 by U46619 was inhibited, suggesting that inhibition of COX-2 expression by cAMP may be downstream of ERK2. Cyclic AMP mitogen-activated protein kinase 1 Homo sapiens