Title : Inhibitory effects of phytopolyphenols on TPA-induced transformation, PKC activation, and c-jun expression in mouse fibroblast cells.

Pub. Date : 1997

PMID : 9290125






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In addition to PKC activation, active oxygen species production, and c-jun induction, our data suggest that TPA treatment induces cellular transformation by other unknown routes, because some tested compounds have an inhibitory effect on TPA-induced transformation but have no or a slight inhibitory effect on PKC activation, active oxygen species production, and c-jun induction. Tetradecanoylphorbol Acetate jun proto-oncogene Mus musculus
2 In addition to PKC activation, active oxygen species production, and c-jun induction, our data suggest that TPA treatment induces cellular transformation by other unknown routes, because some tested compounds have an inhibitory effect on TPA-induced transformation but have no or a slight inhibitory effect on PKC activation, active oxygen species production, and c-jun induction. Tetradecanoylphorbol Acetate jun proto-oncogene Mus musculus