Title : Retinoic acid regulation of the VIP and PACAP autocrine ligand and receptor system in human neuroblastoma cell lines.

Pub. Date : 1997

PMID : 9285932






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Retinoic acid regulation of the VIP and PACAP autocrine ligand and receptor system in human neuroblastoma cell lines. Tretinoin vasoactive intestinal peptide Homo sapiens
2 We sought to determine which receptor gene subtypes are expressed in selected human neuroblastoma cell lines (SH-SY5Y, IMR-32, and LA-N-5), and the effect of RA on the VIP/PACAP ligand/receptor system. Tretinoin vasoactive intestinal peptide Homo sapiens
3 In contrast to RA upregulation of VIP binding (confirmed here in IMR-32 cells), levels of both receptor mRNAs were reduced after RA treatment. Tretinoin vasoactive intestinal peptide Homo sapiens
4 The studies indicate that several components of the VIP/PACAP autocrine system are regulated in neuroblastoma cell lines during RA differentiation. Tretinoin vasoactive intestinal peptide Homo sapiens