Title : Opposite regulation of adenylyl cyclase by protein kinase C in astrocyte and microglia cultures.

Pub. Date : 1997 Sep

PMID : 9282952






1 Functional Relationships(s)
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Protein Name
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1 In astrocytes, a 10-min treatment with the phorbol esters phorbol 12-myristate 13-acetate (PMA) and 4beta-phorbol 12,13-didecanoate (4beta-PDD) (but not with 4alpha-PDD) or with diacylglycerol, which activate PKC, dose-dependently enhanced cyclic AMP accumulation induced by the beta-adrenergic agonist isoproterenol and the adenylyl cyclase activator forskolin. Phorbol Esters protein kinase C, gamma Rattus norvegicus