Title : Lipoic acid reduces the activities of biotin-dependent carboxylases in rat liver.

Pub. Date : 1997 Sep

PMID : 9278559






1 Functional Relationships(s)
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1 This study provides evidence consistent with the hypothesis that chronic administration of lipoic acid lowers the activities of pyruvate carboxylase and beta-methylcrotonyl-CoA carboxylase in vivo by competing with biotin. Biotin pyruvate carboxylase Rattus norvegicus