Title : Prediction of growth sensitivity of acute promyelocytic leukemia cells to granulocyte colony-stimulating factor using 7AAD/PY during administration of all-trans retinoic acid.

Pub. Date : 1997 Aug

PMID : 9277051






4 Functional Relationships(s)
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1 Prediction of growth sensitivity of acute promyelocytic leukemia cells to granulocyte colony-stimulating factor using 7AAD/PY during administration of all-trans retinoic acid. Tretinoin colony stimulating factor 3 Homo sapiens
2 In one patient, APL cells harvested from marrow during the first 3 weeks of ATRA administration showed distinct growth sensitivity to G-CSF ex vivo, and the cells harvested after a 4-week exposure to ATRA appeared to have lost this sensitivity. Tretinoin colony stimulating factor 3 Homo sapiens
3 In this patient, G-CSF could be safely administered after 4 weeks of ATRA therapy. Tretinoin colony stimulating factor 3 Homo sapiens
4 7AAD/PY analysis is useful for predicting growth sensitivity of APL cells to G-CSF during ATRA administration. Tretinoin colony stimulating factor 3 Homo sapiens