Title : c-Myc plays a role in cellular susceptibility to death receptor-mediated and chemotherapy-induced apoptosis in human monocytic leukemia U937 cells.

Pub. Date : 1997 Aug 7

PMID : 9264404






2 Functional Relationships(s)
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1 However, treating the parental U937 cells with antisense oligonucleotides designed to reduce c-Myc expression rendered the cells resistant to etoposide-induced as well as to TNF-alpha-induced apoptosis. Etoposide MYC proto-oncogene, bHLH transcription factor Homo sapiens
2 These results indicate that the reduced expression of c-Myc in UC is strongly associated with the resistance to etoposide-induced apoptosis. Etoposide MYC proto-oncogene, bHLH transcription factor Homo sapiens