Pub. Date : 1997
PMID : 9263351
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Aspirin is an approximately 150- to 200-fold more potent inhibitor of the (constitutive) isoform of the platelet enzyme (COX-1) than the (inducible) isoform (COX-2) which is expressed by cytokines, inflammatory stimuli, and some growth factors. | Aspirin | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 2 | This explains the different dosage requirements of aspirin as an antithrombotic (COX-1) and an anti-inflammatory drug (COX-2), respectively. | Aspirin | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |