Title : An okadaic acid-sensitive pathway involved in the phenobarbital-mediated induction of CYP2B gene expression in primary rat hepatocyte cultures.

Pub. Date : 1997 Aug

PMID : 9262383






2 Functional Relationships(s)
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1 We have previously demonstrated that specific activation of a cAMP-dependent protein kinase A (PKA) pathway resulted in complete repression of phenobarbital (PB)-inducible CYP gene expression in primary rat hepatocyte cultures. Phenobarbital cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 Rattus norvegicus
2 We have previously demonstrated that specific activation of a cAMP-dependent protein kinase A (PKA) pathway resulted in complete repression of phenobarbital (PB)-inducible CYP gene expression in primary rat hepatocyte cultures. Phenobarbital cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 Rattus norvegicus