Title : Specific binding of 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl propyl) piperazine (GBR-12935), an inhibitor of the dopamine transporter, to human CYP2D6.

Pub. Date : 1997 Jun 15

PMID : 9256169






2 Functional Relationships(s)
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1 The binding of [3H]GBR-12935 to CYP2D6 was decreased partially by substrates or inhibitors of CYP2D isoforms (quinine, quinidine, propranolol, bufuralol, imipramine, and desipramine). Imipramine cytochrome P450 family 2 subfamily D member 6 Homo sapiens
2 The binding of [3H]GBR-12935 to CYP2D6 was decreased partially by substrates or inhibitors of CYP2D isoforms (quinine, quinidine, propranolol, bufuralol, imipramine, and desipramine). Imipramine cytochrome P450 family 2 subfamily D member 6 Homo sapiens