Title : Preservation of endogenous antioxidant activity and inhibition of lipid peroxidation as common mechanisms of antiatherosclerotic effects of vitamin E, lovastatin and amlodipine.

Pub. Date : 1997 Aug

PMID : 9247534






1 Functional Relationships(s)
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1 OBJECTIVES: We sought to document the common mechanisms of the antiatherogenic effects of the cholesterol-lowering hydroxy-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor lovastatin, the dihydropyridine Ca2+ blocker amlodipine and the antioxidant vitamin E. Lovastatin 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oryctolagus cuniculus