Pub. Date : 1997 Jun
PMID : 9241755
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In vivo, epinephrine and the vasopressin analog DDAVP increase vWf plasma levels, although they are thought not to induce vWf release from endothelial cells in vitro. | Epinephrine | von Willebrand factor | Homo sapiens |
| 2 | Epinephrine (together with IBMX) caused a small, dose-dependent increase in vWf release, maximal at 10(-6) M (+50%), and also potentiated the response to thrombin. | Epinephrine | von Willebrand factor | Homo sapiens |
| 3 | We found a close correlation between cellular cAMP content and vWf release after stimulation with epinephrine and forskolin. | Epinephrine | von Willebrand factor | Homo sapiens |
| 4 | These results demonstrate that cAMP-dependent signaling events are involved in the control of exocytosis from endothelial cells (an effect not mediated by an increase in [Ca2+]i) and provide an explanation for epinephrine-induced vWf release. | Epinephrine | von Willebrand factor | Homo sapiens |