Title : Phenobarbital causes apoptosis in conditionally immortalized mouse hepatocytes depending on deregulated c-myc expression: characterization of an unexpected effect.

Pub. Date : 1997 Jul 15

PMID : 9230198






1 Functional Relationships(s)
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1 Interestingly, subsequent introduction of an activated c-H-ras oncogene into the c-myc-transfected CHST8 cells resulted not only in escape from the growth arrest at 39 degrees C but also in complete inhibition of the phenobarbital-inducible apoptosis along with de novo induction of the Bax antagonist, Bcl-2. Phenobarbital Harvey rat sarcoma virus oncogene Mus musculus