Title : Engineering the human thyrotropin receptor ectodomain from a non-secreted form to a secreted, highly immunoreactive glycoprotein that neutralizes autoantibodies in Graves' patients' sera.

Pub. Date : 1997 Jul 25

PMID : 9228077






1 Functional Relationships(s)
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1 This ectodomain variant was partially purified using sequential lectin and nickel-chelate chromatography, permitting the first direct visualization and quantitation of the mammalian TSHR. Nickel thyroid stimulating hormone receptor Homo sapiens