Title : Fate of insulin analogs in intact and nephrectomized rats determined by their receptor binding constants.

Pub. Date : 1997 Jun

PMID : 9227456






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1 After intravenous injection of 125I-labeled human insulin and analogs in normal and nephrectomized rats, we examined their kinetic fate by Q-Sepharose separation into intact ligand, "fragments" (genuine fragments and protein-bound radioactivity), and iodide. Iodine-125 insulin Homo sapiens