Title : Thyroid regulation of NADPH:cytochrome P450 oxidoreductase: identification of a thyroid-responsive element in the 5'-flank of the oxidoreductase gene.

Pub. Date : 1997 Jul

PMID : 9224811






1 Functional Relationships(s)
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1 The current study demonstrates that T3-activated transcription of the NADPH:cytochrome P450 oxidoreductase (P450R) gene is dependent on the thyroid hormonal status of the animal, with both transcriptional and post-transcriptional pathways being important in regulating the cellular P450R mRNA level. NADP cytochrome p450 oxidoreductase Rattus norvegicus