Title : Chemical chaperones correct the mutant phenotype of the delta F508 cystic fibrosis transmembrane conductance regulator protein.

Pub. Date : 1996 Jun

PMID : 9222597






1 Functional Relationships(s)
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1 Treatment of the delta F508 CFTR-expressing cells with any one of these compounds, which we now refer to as "chemical chaperones", restored the ability of the mutant cells to exhibit forskolin-dependent chloride transport, similar to that observed for the cells expressing the wild-type CFTR protein. Colforsin CF transmembrane conductance regulator Homo sapiens