Title : Human sleep EEG following the 5-HT1A antagonist pindolol: possible disinhibition of raphe neuron activity.

Pub. Date : 1997 Jun 6

PMID : 9219866






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1 Human sleep EEG following the 5-HT1A antagonist pindolol: possible disinhibition of raphe neuron activity. Pindolol 5-hydroxytryptamine receptor 1A Homo sapiens
2 The EEG power spectrum induced by pindolol tended to be opposite to what has previously been reported for ipsapirone, a 5-HT1A agonist. Pindolol 5-hydroxytryptamine receptor 1A Homo sapiens
3 Therefore, the present data, tentatively, are consistent with the contention that pindolol inhibits, possibly selectively, somatodendritic 5-HT1A autoreceptors in humans and may antagonize self-inhibition of midbrain raphe nuclei 5-HT neurons. Pindolol 5-hydroxytryptamine receptor 1A Homo sapiens