Title : Transcriptional regulation of prostaglandin-H synthase-2 gene in human trophoblasts.

Pub. Date : 1997 Jul

PMID : 9215309






4 Functional Relationships(s)
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1 In response to either 12-0-tetradecanoylphorbol-13-acetate (TPA) or 8-bromo-cAMP, we observed an increase in PGHS-2 promoter activity but no change in activity of PGHS-1 promoter. Tetradecanoylphorbol Acetate prostaglandin-endoperoxide synthase 2 Homo sapiens
2 Aspirin attenuated the stimulatory effect of TPA on PGHS-2 promoter. Tetradecanoylphorbol Acetate prostaglandin-endoperoxide synthase 2 Homo sapiens
3 The activity of PGHS-2 promoter is stimulated by either TPA or cAMP, and the stimulatory effect of TPA is attenuated by aspirin. Tetradecanoylphorbol Acetate prostaglandin-endoperoxide synthase 2 Homo sapiens
4 The activity of PGHS-2 promoter is stimulated by either TPA or cAMP, and the stimulatory effect of TPA is attenuated by aspirin. Tetradecanoylphorbol Acetate prostaglandin-endoperoxide synthase 2 Homo sapiens