Pub. Date : 1997 Apr
PMID : 9209412
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The role of erythropoietin receptor tyrosine phosphorylation in erythropoietin-induced proliferation. | Tyrosine | erythropoietin | Mus musculus |
| 2 | The role of erythropoietin receptor tyrosine phosphorylation in erythropoietin-induced proliferation. | Tyrosine | erythropoietin | Mus musculus |
| 3 | Although studies with truncated erythropoietin receptors (EpoRs) have suggested the tyrosine phosphorylation (Yphos) of the EpoR may not play a significant role in Epo-induced proliferation, we found, using a full length EpoR mutant designed Null, in which all 8 of the intracellular tyrosines (Ys) were substituted with phenylalanines (Fs), that Null cells required 5-10 fold more Epo than wild type (WT) EpoR containing cells in order to proliferate as well. | Tyrosine | erythropoietin | Mus musculus |