Title : Conditional expression of the mitogen-activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells.

Pub. Date : 1997 Jul 4

PMID : 9202001






1 Functional Relationships(s)
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Protein Name
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1 This differential substrate specificity of MKP-1 can be functionally extended to nuclear transcriptional events in that PMA-induced c-Jun transcriptional activity was more sensitive to inhibition by MKP-1 than either Elk-1 or c-Myc. Tetradecanoylphorbol Acetate MYC proto-oncogene, bHLH transcription factor Homo sapiens