Title : Pretreatment with phorbol ester and an LHRH agonist reduces testosterone production and protein kinase C activity in rat Leydig cells challenged with PDBu and LHRH.

Pub. Date : 1996 Nov

PMID : 9196561






3 Functional Relationships(s)
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1 Pretreatment with phorbol ester and an LHRH agonist reduces testosterone production and protein kinase C activity in rat Leydig cells challenged with PDBu and LHRH. Phorbol Esters protein kinase C, gamma Rattus norvegicus
2 We conclude that down-modulation of protein kinase C by prolonged exposure of Leydig cells to phorbol esters or LHRH-A results in decreased PK-C activity and testosterone secretion. Phorbol Esters protein kinase C, gamma Rattus norvegicus
3 We conclude that down-modulation of protein kinase C by prolonged exposure of Leydig cells to phorbol esters or LHRH-A results in decreased PK-C activity and testosterone secretion. Phorbol Esters protein kinase C, gamma Rattus norvegicus