Title : Endogenous fibronectin of blood polymorphonuclear leukocytes: stimulus-induced secretion and proteolysis by cell surface-bound elastase.

Pub. Date : 1997 May 25

PMID : 9184073






1 Functional Relationships(s)
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1 Kinetic studies indicated that fibronectin was rapidly secreted as an intact molecule and that proteolysis started within minutes and proceeded for at least 1 h. If cells were removed after 5 min TPA treatment, no further proteolysis of the secreted fibronectin was observed, indicating participation of cell-bound proteinases. Tetradecanoylphorbol Acetate fibronectin 1 Homo sapiens