Title : Consistent allelic loss on mouse chromosome 7 distal to tyrosinase in 4-nitroquinoline-1-oxide-induced oral cavity tumors with loss of heterozygosity at Ha-ras-1.

Pub. Date : 1997 May

PMID : 9180923






3 Functional Relationships(s)
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1 We have previously shown that all CBA/J mice exposed to 4-nitroquinoline-1-oxide (4NQO) eventually develop oral cavity squamous cell carcinomas, and two-thirds of these tumors have Ha-ras-1 (Hras1) point mutations at codon 12. 4-Nitroquinoline-1-oxide Harvey rat sarcoma virus oncogene Mus musculus
2 We have previously shown that all CBA/J mice exposed to 4-nitroquinoline-1-oxide (4NQO) eventually develop oral cavity squamous cell carcinomas, and two-thirds of these tumors have Ha-ras-1 (Hras1) point mutations at codon 12. 4-Nitroquinoline-1-oxide Harvey rat sarcoma virus oncogene Mus musculus
3 We have previously shown that all CBA/J mice exposed to 4-nitroquinoline-1-oxide (4NQO) eventually develop oral cavity squamous cell carcinomas, and two-thirds of these tumors have Ha-ras-1 (Hras1) point mutations at codon 12. 4-Nitroquinoline-1-oxide Harvey rat sarcoma virus oncogene Mus musculus